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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1452012331a3ceb8c3cf18663f4f0d15ea099a24e559c3c404b4fdc2d06b2c75' 
  AND token = 'xSf8J9ZZcLENZIlw4KIIzCimNco4zM5nGs5vLG5sJ8Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}