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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3368932b68566ec978b37bcb2ee510bedd7aacd9a9a17e809dc1960e56262069' 
  AND token = 'ChTTOVqqWS9LWoi8sSQtPl5JP0e/mXH4WMtrDCGb2jk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}