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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0cc4d545babb42b8a8b39100e53eb006b89e3a8f07118c26728549ee364a772' 
  AND token = 'yGf7Kb88UpHv5w+dpu0wOtlIIWVpUVfhuf3z80s1M50=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}