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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '220e0ab4114a1c43942562d4b7498234e2d520e2a22e0faef95b3a993302a126' 
  AND token = 'nVb2sZkqR+wVo1qtOX3ALvDH5nA21/9mfz3Y/K0FmR0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}