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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77798a432b860d4037c72450e7acc9eef0b0992c0218141771fb8c98d798c43c' 
  AND token = 'T7sOvC/cNLVUDHoZJt2OLhveHGKVtdr0xyBYyv2s9qo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}