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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e98a080e1de8f74bf1c322e781f8e3d996833348563b219024bb617963890b4' 
  AND token = 'cZ4BE1yiKgnTpP0pjNkzwG1LovyxAPPPxRqHP8OWcAw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}