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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6cdde0b7cdfb17541343f70265c420b9eec61825062615a99eee1d152784b4c1' 
  AND token = '3Ax8INiTf5o9ym269hARaGf4CHyeiG6jQVG2O1CGZuc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}