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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '07710fdbd58e63874ee49eabb9a6fd4f2679b702bf93bf0e38ca979495275101' 
  AND token = 'pcJJxDJBGaRf+MOqw9Iv8C9LsaC0GE2Xi34rP8fbjU8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}