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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99b7a1cd48b3fe77a64a4236f610bd17553b07fa477296d34634139523c18cfd' 
  AND token = 'mUBPUeCZM1TtA/hLninpOHePSoOeqJppEgirDraoi5I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}