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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e45fba839acbfbc82a8937d912730e778e974b70a1b70fde0528bf44eb96677' 
  AND token = '4NU1sD5Tly4HnqwO3NX/jv4RUCiHrjYUljyQDW9h6ls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}