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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e56cc2cc38432e87ecaa4fdfe740dbf2abb4f58571598368d7da9224ab19c86b' 
  AND token = 'fhR2t2xRGb+Bx1zbhRCi7ZDm/yW+4dQENyEyplFdFBo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}