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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c9b4cef549c90f11ed72c1df99ceb6f1886e913f603681902ed810204ac05569' 
  AND token = 'HyBtIDwLQKnaccLo3PdsAvb/Ww0aY29I4CxC2Qv0BDg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}