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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '586251e899cb95cf8f32f28bf105ef9c6dedcbc709cb9cf6849b64158fd16370' 
  AND token = 'gHiBlBcpSrPSiCz/8xFaK02MOQksFKD35ZpuVgcVgO4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}