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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8fe66737e71bbad1719e580864d12b0c678b76b837a03ad0d62418773392d3e' 
  AND token = 'bJRFIovIp4jm2qzapHki8e3jbzt5jF8sr0xaMSGgAfc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}