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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3397007f9a0684e01e8d0b0cd4d695a6988f8f3968171fea7ae975e557bdb0b2' 
  AND token = 'pzKLVwpjUEnTQIfirV3+P8xFOA3DHAG8SHTQBkdfN1M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}