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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0f0386d48f92169a0f83af7c8b97c83fe22770b78de4cf02e6a1428a57d60f8' 
  AND token = 'y0js272wTCXPKu74xYydyWznh2j4XgwmNb0+xESmink=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}