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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9da76014101da25bc23a3e27be3e59eb29482029a161f4b70065d36f2bffe5b' 
  AND token = 'uuSyD6YXZuYFWzW9Jlhu1hLePs2H297Ozt9Dd9yNhgw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}