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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72fa73427adfc8345ff693caf8efa3d3f43e0aff1292b5eed0b16eead5f13b9a' 
  AND token = 'Q3PlkONjcWD4d59MS+wJsX6UxrQc33bohF/P7I5FqzU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}