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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f2456904d5b300379e164b7aea018762bd906b83d93c031b9370ea6f081c1a3' 
  AND token = 'H8rs/FlPC/kmqfnscCgBTNEX+czjRMvB7V17eO5fFgM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}