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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '526ccdac34d0154297cd10456f16d0fbabe336e961e296d8f7fc25b15d48490b' 
  AND token = 'XOqf4Rv6j3dwyQxTxvfalqWN5TsIbM6YCHPbm2CM2Lc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}