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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b1d9d03f182464694141eae0fc261ea0ccfc6cc2096c01a53c4dfa64c71e09d' 
  AND token = '4nIoSPZ3SBPFl/vXiXLV6N5h2PGddqtmk1XEsBGcKR0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}