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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0834fb5497f5e365aef590cd2d29d78cb2deb2c00446e50a54a02744414c035' 
  AND token = 'aX+Aem9IXKDEVg76IFnPk8aMkewFYelTa0y42vC3hKc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}