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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9861cb17531a05781b606cd14061dc69545d2af02d746def75737a9fc8d3b8c2' 
  AND token = '1ULDXO79b36El9GvTCrTBwErww6O1d+9GU1ulKTvoyA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}