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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4cb8f780617832cb3f201ff38bb655346be9df82845f836494180cc641badf2' 
  AND token = 'XWS/88lPDP8JLhMEDMl58jGoBW4QZMF48t8fvV4+w70=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}