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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a66b6722f9f8522085ce332345101d151c357a46a3f97f858d7f94e42a4e0904' 
  AND token = 'x+QbDP1iu3pgTuCZw573emSm8vNvLd4IJZStTXbCJSs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}