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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '758ae4bb61f8136e896b3014f0756763fc5d69dc386506d8e6fed5cc3753398d' 
  AND token = 'P2U9osjfzSjHhQHO3D8Shhd0Ii+2U7Ic7eroDA5wDtM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}