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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de014bf815e3cafccb08c5659e691aae0c75b83cecc85d2481420b93243b3e4b' 
  AND token = 'ddrfHNHXO/UealZTXiVB0Z1BOqhfa3GT0d6sYhn/ufQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}