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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6dff817f4f4040e22009a8155a98c1fa4cffe28e2b10b27b7187318e8c1be625' 
  AND token = '6Q6veV0LADeCK/nCk/kmGCTlZkj0j8OoYZrYgmR4Anc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}