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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecf3f9f2b66665de7e9ba79fcb425dda57aeb05316242932a73dfa3977b74f39' 
  AND token = 'k8v+EmOHjQrpvikym7YuAOIvGTCmyM6We9Uw5j2dArM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}