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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c22fbbcc69d7a117c59ad4e83e12c3ffe72f438d462141b744ebc96e20bdff7' 
  AND token = 'GMayg7B0UKSC5u/wfeza/teGiL4jlRaFwcTFtMpeWLs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}