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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4eed284899adefc9460a95dee95521d6ee6ef27d70b2fd440d9eb1cd8169424e' 
  AND token = 'Cgk0riE2b9/8LK4vpMuvsezGTUo7p55qT+o35prbW80=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}