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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '382318b0d9985d9f77e8b3ba9e3fdfae307066b147b91a069de72775655a9767' 
  AND token = '4cv3pHEgXekQziG11v4+jPLjM35gYxu3A/toVplQAyY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}