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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '55965e2f45c40acb4b4b6ab33bde7a1b36f77cd627eed133ac9d4c7a51dd8893' 
  AND token = 'm00bONU7X/nD28bveJnKc8kMgS0kEbTls79a+/IjJmg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}