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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2202ec67c35bee1d3dfb0423429ee81f6a1147f3a4d406927aca1c9ec8df9b07' 
  AND token = 'UGFOxPrbw9R2wTyVDHMFhpVLcY/clqLgO5qtNk7wS0g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}