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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '269dbeb4f82e8827bb565d2f18ee5898091e096b27c8d03c9058b5295a8385f0' 
  AND token = 'GwhJFGr/tRGPIkFi6QFQo+Pou1elOdfE2EGC6QDUY3Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}