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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50ee17b5cd6ddfc4f0146499869e8da143e5c86315129b8c1fe6d15c9fd50556' 
  AND token = 'RhWBHid+rvpeVVlU2HOOTlD3Ac+spcBtmBUQcOL3GGU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}