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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4da4bf4f650b6bbb941dd5d8c31c2c9ac5a92fb950d24d61d1c983b308f67d8d' 
  AND token = 'PiPbXjXlakGkxPTcufdKK0xHhV84U5PbaNe0RjkxENQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}