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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1b27804e7b61d739885bdcaf8428e1d01553769a2d3bfac689865353d07b2da' 
  AND token = 'VvyPUZk40V0Uj18Jcc1aRitxlIxJUzQ4Iik7AJ7lTo4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}