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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73f2dab8697b9e4ebc54628bff184b43fe9f1663edd0f0d4061f93e93f253174' 
  AND token = 'EL+kTQs24V4Z0ozSA2yIx8mo5/I5c4WrQyVHymMcoh8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}