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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a8379206a804377dd1033a09640302b957b9ad653711a90cb278cc50ae354c6' 
  AND token = '4vOWPAptacCuvpgrLxYVTecyrSNku11PxmsV5ZVOukI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}