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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2ab618baf17e8a7a6747a6f243716b36e76ff48a02162afd34cef20c42df35d' 
  AND token = 'JHSC6hYa75WfPtLI1L4fz42vJbzbyPoXRm2crm4SMng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}