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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5c8d02f238aa5a9494472bcbe08fe7443dec3afca380521ebdc1397d4f96369' 
  AND token = 'OSQth8U3up14zEYU9TWSocc8aMN1nocTEPc2g5q9rnY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}