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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15cb44ea5f61dc10129fe241559c6747e550c314ccc83b2e8e60a24726c34549' 
  AND token = 'Fe3gG9bct3hZIL9wjM+Ol7dUG+kq7TxNQVDDPakYRF8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}