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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d80c02c6b69cc419e54bf68c756059f1c8a0fcf44a22e21b5d26da2dea95471' 
  AND token = '+zovccJCFTMM0LZNAesoLt2EXUHmXzPgYG0/tp+mLPk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}