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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb41f39ef37e358a5a9dfba91c79f91851f1e7c6ccbb6a538a1227b5f68e98aa' 
  AND token = 'M2Uv4OJAPSeyqHW+m5541jQsclE3h4Q3K31ENCG+IpA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}