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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed5183e5c25a78e497553041ec02d41b1b8350e15970ac5c9e487090948fa7c4' 
  AND token = '+B22cU2AJPNrfWQPWdjHJaa/2JPPlLW9gOJvcXWyO7Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}