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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f372d8865031c892a4f6382a8d20afbe3a2cea50336e858166bf0db617ca41d' 
  AND token = 'xu+/FwWEu8r8H1sqHckeq0bTWkyNYW2Nze7CN8bQcM8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}