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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a83381fc00aff2658a60e0d7aa8afaa33776273d90bb3fc99df9125c9203cb4' 
  AND token = 'uSKzItvPKX34IpTwRsAiZ4exZRd4jxGXkMlKUOe3iAc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}