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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ec780af472e557c117d4ed8b98858ff8c370e561c369a79686596b01f747be3' 
  AND token = 'O0GLTj4AG5ax6b3KlgQASY2z4qk3q3MlX3B46i/TjPg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}