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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f709ab250034af11d015c1eb7c0832b8c2c66bc2f0be139e5bc37d983c4a7df' 
  AND token = 'qT0QMz4ZKCT0gC4APeSuALTHe2+1hYgM2hnnCpjibGs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}